Sarkoidosis

Hvala Laki na iscrpnim odgovorima.
Ja jos ne znam da li ce diagnoza biti sarkoidosis posto za sada jedini organ koji ima nekih tragova je palable lump na desnog dojci ( sto nije cesto, skoro nikako opisano u ovoj bolesti), a biopsijom je utvrdjeno prisustvo "acute and chronic mastitis with non-casearing granuloma" . x=ray Pluca cist - nema nikakvih tragova. Sledece nedelje imam zakazan pregled kod specijaliste. Doktor opste prakse je posumnjao na ovu bolest, mada nije uspostavio jos nikakvu dijagnozu.

Sarkoidoza-bolest karakterizirana nekazeificirajuæim granulomima. Može se pojaviti u bilo kojoj dobi ili u bilo kojem organu, ali najèešæe zahvaæa pluæni parenhim u mlaðih odraslih osoba. Klinièka slika: akutni oblik (Lofgrenov sindrom) karakteriziraju erythema nodosum, bilateralna hilarna limfadenopatija, poliartralgija; podmukli poèetak najèešæe se prezentira uz bilateralnu hilarnu limfadenopatiju uz poremeæaje dišnog sustava, ali i sistemskih poremeæaja slabijeg stupnja kao što su neproduktivan kašalj, slabost, osjeæaj iscrpljenosti, gubitak tjelesne težine, limfadenopatija, hepatosplenomegalija. Ekstratorakalni znakovi sarkoidoze: 1. koža- erythema nodosum, lupus pernio 2. oèi-hipopion, uveitis 3. kosti-artralgija 4. srce-ventrikulna tahikardija, kompletni srèani blok, kongestivna kardiomiopatija, srèana dekompenzacija 5. CNS-paraliza kranijalnih i perifernih živaca 6. bubreg-hiperkalcemièna nefropatija, bubrežni kamenci.

PS.Evo jos nesto u vezi gore pomenute bolesti! Nastojacu da saznam koje bi biljke
mogle pomoci kod ove bolesti jer me to sada jako zanima. Laki

Ovo je tekst sa interneta pa ako dobro poznajete engleski nadam se da ce te usporediti
sa simptomima bolesti za koju sumnja doktor kojeg ste naveli! L

MULTIPLE SCLEROSIS (MS) AND SARKOIDOSIS ONE ENTITY ?

Background: The two illnesses MS and sarkoidosis appear to have several things in common. They both are autoimmune diseases affected by infectious agents and present relapsing and remitting MS affects the central nervous system while sarkoidosis is granulomatous a disease that among others parts attacks the nervous system also. The coexistence of the two diseases in one patient lends to the question whether the two diseases are in actuality one.

Case report: The patient is a female, 52 years old of age with a mild form of chronic MS first diagnosed 15 years ago. Within a period of months she appeared to have suffered from loss of weight, abdominal pain, fatigue, inability to walk, difficulty in breathing ataxia, dysphasia and various aesthetic disturbances. The clinical examination showed dapple vision, horizontal nystagmous a mild spastic tetraparesis with babiski positive and scattered sensoric disturbances. Beyond that a pulmonary infiltration was found and palpably liver.

The clinical and neurological and neurophysiological examination…… confirmed the already known existence of MS. The liver tests showed an increase in transaneminase. Scanning with 6A 60-67 showed granulomatous pulmonary infiltration with hilar lympadenopathy (lunges and liver biopsy alterations granulomatous of the sarkoidosis type). After treatment of immunosuppressive and intravenous immunoglobulines there was an improvement in the typical symptoms of both diseases.

Discussion: Neither MS nor sarkoidosis present problems in diagnosis as a rule. While the first attacks the CNS the second assaults various body parts. It may be however that due to the nature of the clinical picture, one may be hiding the other which makes diagnosis harder. However, the autoimmune origin, the sameness of the clinical behvour and the fact that the immunosupressive treatment generated a parallel improvement in the patients leads to the possibility of a unified entity of the two illneses. This is however an observation that will require more research, and should make us have careful when diagnosis MS about the existence of more autoimmune problems.

Abstract published in abstract book of EUROPEAN SOCIETY OF THORACIC IMAGING, 6th Annual meeting.

paper presented at the EUROPEAN SOCIETY OF THORACIC IMAGING, 6th Annual meeting, Bologna, Italy, June 14-16, 1998